μετα 2010

Second International Workshop on Metacomputation in Russia
 

July 1-5, 2010, Pereslavl-Zalessky (120 km to the north-east from Moscow), Russia

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Programming in Biomolecular Computation

Invited Talk

Lars Hartmann, Neil D. Jones and Jakob Grue Simonsen,
Department of Computer Science, University of Copenhagen (DIKU), Denmark

 

Abstract

Full text pdf 463 KB

Our goal is to provide a top-down approach to biomolecular computation. In spite of widespread discussion about connections between biology and computation, one question seems notable by its absence: Where are the programs? We introduce a model of computation that is evidently programmable, by programs reminiscent of low-level computer machine code; and at the same time biologically plausible: its functioning is defined by a single and relatively small set of chemical-like reaction rules. Further properties: the model is stored-program: programs are the same as data, so programs are not only executable, but are also compilable and interpretable. It is universal: all computable functions can be computed (in natural ways and without arcane encodings of data and algorithm); it is also uniform: new "hardware" is not needed to solve new problems; and (last but not least) it is Turing complete in a strong sense: a universal algorithm exists, that is able to execute any program, and is not asymptotically inefficient.
A prototype model has been implemented (for now in silico on a conventional computer). This work opens new perspectives on just how computation may be specified at the biological level.



Presentation pdf 460 KB

References mentioned in the presentation: